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Detection of single and multiple targets in tissue phantoms using fluorescence-enhanced optical imaging

Radiology, 235, 148-154, 2005


Status: Published

Citations:

Cite: [bibtex]


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Abstract: Imaging plays a central role in cancer diagnosis, therapy, and prognosis primarily through the depiction of anatomically defined abnormalities. With the wealth of information provided by the maturing fields of genomics and proteomics, the identification of molecular markers and targets promises contrast material–enhanced diagnostic imaging with specificity and sensitivity that is not otherwise possible with conventional anatomic imaging. If measurement approaches can result in the acquisition of signals from micromolar or smaller amounts of contrast agents within clinically relevant volumes, molecular imaging promises to improve diagnostic imaging and to affect the quality of care for patients with cancer.



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